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KW-2449 mediates cytotoxicity thru inhibition of FLT3/ITD
7-trien-2-one
Vanderbilt A
Limaprost is orally active
ABBV-744 - CAS# 2138861-99-9 48671 KW-2449 mediates cytotoxicity thru inhibitionABBV 744 is a first in class, orally active and selective inhibitor of the BDII domain of BET family proteins with IC50 values range from 4 to 18 nM for BRD2, BRD3, BRD4 and BRDT. ABBV 744 is primarily metabolized by CYP3A4 with drug like properties enable the investigation of its antitumor efficacy and tolerability. Product information CAS Number: 2138861 99 9 Molecular Weight: 491. 55 Formula: C28H30FN3O4 Chemical Name: N ethyl 4 [2 (4 fluoro 2,6
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